Characteristics N Person months/100 Malaria cases Rate/100 person months Crude Rate ratio (95%CI) Adjusted rate ratio (95%CI) P-values LR
Age group <5years 133 7.16 94 13.14 1 1    
5-15years 270 14.56 115 7.90 0.60 (0.46-0.79) 0.73 (0.52-1.02) 0.065  
>15 years 234 12.50 25 2.00 0.15 (0.10-0.24) 0.23 (0.14-0.40) 0.001  
Ethnic group Fulani 225 7.03 87 12.37 1 1    
Mandinka 201 6.90 73 10.58 0.98 (0.72-1.34) 0.56 (0.36-0.87) 0.009  
Wolof 200 6.46 69 10.68 0.92 (0.67-1.26) 0.68 (0.45-1.01) 0.059  
EIR Low 90 5.17 20 3.87 1 1    
Medium 409 21.87 154 7.04 1.82 (1.14-2.90) 2.15 (1.23-3.78) 0.008  
High 138 7.18 60 8.35 2.16 (1.30-3.58) 2.54 (1.29-4.97) 0.007  
Bed net No 473 25.36 164 6.47 1 1    
Yes 164 8.87 70 7.89 1.22 (0.92-1.61) 1.14 (0.82-1.59) 0.435  
Eaves Gap No 284 15.42 98 6.36 1 1    
Yes 353 18.81 136 7.23 1.14 (0.88-1.47) 1.26 (0.92-1.74) 0.150  
Sickle cell genotype AS 465 6.33 26 4.11 1 1    
AA 117 25.02 184 7.36 1.79 (1.19-2.70) 1.62 (1.05-2.51) 0.030  
SS 7 0.38 5 13.15 3.20 (1.23-8.33) 2.47 (0.91-6.69) 0.076  
G6PD deficient No 570 30.53 211 6.91 1 1    
Yes 32 1.71 6 3.51 0.51 (0.23-1.14) 0.47 (0.21-1.09) 0.079  
AMA1 Total IgG 0 276 14.85 139 9.36 1 1    
>0 <260 87 4.69 35 7.46 0.80 (0.55-1.15) 1.20 (0.78-1.85) 0.399  
260-729 88 4.73 18 3.80 0.41 (0.25-0.66) 0.67 (0.39-1.15) 0.143 X2=12.19
P=0.0160
730-1100 87 4.65 24 5.16 0.55 (0.36-0.85) 0.98 (0.58-1.65) 0.942  
>1100 88 4.72 9 1.91 0.20 (0.10-0.40) 0.37 (0.17-0.79) 0.010  
MSP119 Total IgG 0 205 10.96 104 9.49 1 1    
>0 <60 105 5.58 55 9.85 1.04 (0.75-1.44) 1.23 (0.82-1.85) 0.312  
61-220 106 5.70 38 6.67 0.70 (0.48-1.02) 0.96 (0.63-1.46) 0.850  
221-840 105 5.64 18 3.19 0.34 (0.20-0.55) 0.43 (0.23-0.81) 0.008 X2=15.15 P=0.0044
>840 106 5.82 11 1.89 0.20 (0.11-0.37) 0.52 (0.26-1.03) 0.062  
CSP Total IgG 0 153 8.19 67 8.18 1 1    
>0 <200 117 7.31 46 6.29 0.89 (0.61-1.30) 1.12 (0.74-1.70) 0.592  
210-600 118 4.85 31 6.40 0.59 (0.39-0.91) 0.78 (0.49-1.25) 0.306 X2=4.75
P=0.314
601-1050 118 7.45 47 6.31 0.91 (0.63-1.32) 1.15 (0.75-1.76) 0.513  
>1050 118 5.51 35 6.35 0.67 (0.45-1.01) 0.79 (0.49-1.27) 0.337  
  TOTAL 640 34.22 234 6.84        
LR: Logistic Regression; CI: Confidence Interval; X2: Chi squared; P: p-value; N: Number of individuals tested
Table 2: Baseline characteristics of the cohort study subjects at enrolment and malaria incidence in association with AMA1, MSP119 and CSP total IgG antibody levels adjusted for confounders.