Groups   No. Percentage of CD4+ CD25+ FOXP3+ P value TH 17% P value
Mean ± SD Mean ± SD
Control 50 1.72 ± 1.27   0.61 ± 0.25  
Group (I) 14 1.80 ± 0.83 >0.05 1.09  ±0.74 >0.05
Group (II) 48 1.49 ± 1.00 >0.05 1.19 ± 0.34 <0.001*
Group (III) 38 1.01 ±  0.87 <0.001* 1.62 ± 0.73 <0.001*
*p value = 8.6 × 10-4<0.001 Highly Significant.
Th17% p values were 0.07NS for group I; 9 × 10-4 HS for group II and 7.1 × 10-4 HS for group III
p values of each group are in comparison to control group.
Table 4: Frequencies of circulating CD4+ CD25+ FOXP3+, Th17+ cells in RA patients and controls.