Protein Expression in:   Cancer Stage Histo-logy Anti-CD3 response rIL2 Treatment Response Response Responder Non-Res ponder +ve -ve Bad Good TCRξ ↓ →Controlto stage III ↓stage IV ↓ ↑ ↓ → → ↓ ↑ CD3ℰ ↓ → → ↑ ↓ → → → → LCK ↓ → → → → → → → → ZAP-70 ↓ ↓ → ↑ ↓ ↑ ↓ ↓ → PKC → → → ↑ ↓ → ↓ → →

Table 1: Table showing the status of T cell signal transducing proteins in response to stimulation by antiCD3 and augmentation with rIL-2 [3].