Figure 1: Antibodies co-localize with Stress Granules in SK-N-SH neurons. SK-N-SH cells were seeded into 8 chamber slides. Cells were treated with either anti-hnRNP A1-M9 antibodies, IgG, or left untouched. Following a 48 hr incubation, cells were fixed with 4% Paraformaldehyde, blocked and permeabilized, and stained for stress granules with anti-TDP-43 antibodies. The figure shows that both antihnRNP A1-M9 antibodies and control IgG (arrows) cause stress granule formation and colocalize to stress granules.