| Autoimmune Diseases |
HLA Molecule |
Strength of Association |
| Ankylosing spondylitis |
HLA-B27 (Caucasians) |
++++ |
| Rheumatoid arthritis |
HLA-DR4
HLA-DRB1*04 |
+++ |
| Systemic lupus erythematosus |
HLA-DR2, DR3 |
++ |
| Sjögren's syndrome |
HLA-DR3 |
++ |
| Psoriatic spondylitis |
HLA-B27 |
+++ |
| Dermatitis herpetiformis |
HLA-DR3 |
+++ |
| Gluten-sensitive enteropathy (celiac disease) |
HLA-DQ2 |
+++ |
| Type 1 diabetes mellitus |
HLA-DR3, DR4, DQ2, DQ8 |
+++ |
| Hyperthyroidism (Graves') |
HLA-DR3, B8 |
+ |
| Hashimoto’s Thyroiditis |
HLA-DR3, DR5 |
++ |
| Adrenal insufficiency |
HLA-DR3 |
++ |
| Myasthenia gravis |
HLA-B8, HLA-DR3 |
+ |
| Multiple sclerosis |
HLA-DR2 |
++ |
|
