Figure 4: Effector CD4+T cells and CD8+T cells in peripheral blood samples. (A) Scatter plot with median of the percentage of effector CD4+T cells (left Y axis)
and CD8+T cells (right Y axis) that expressed IL-17, IL-2, IFN-γ, IL-6, TGF-β, TNF-α, IL-10 or IL-1β in T1D children, siblings and controls. *, P < 0.05; **, P < 0.01. (B)
Percentages of CD4+T cells expressing IL-17 and percentages of CD4+T and CD8+T cells expressing IL-2 correlated with age, age of diagnosis and disease duration
in T1D children (Spearman P and r value).