T1D Siblings Controls Significance Value
Number 26 32 29  
&Male 15 (58%) 16 (50%) 14 (48%) 0.43
#Age (yrs) 12.25 (6.30) 11.75 (6.36) 8.18 (7.74) 0.25
#Disease duration (yrs) 2.95 (4.45)      
Autoantibody
&GADA 15 (83%) 4 (14%)    
&IA-2A 14 (82%) 1 (4%)    
&GADA&IA-2A 14 (82%) 1 (4%)    
Blood Count (x106/ml)
RBC 4790 (235) 4670 (360) 4560 (455) a*
#WBC 6.30 (1.37) 6.23 (1.34) 9.05 (3.14) a***, b***
#Lymphocytes 2.62 (0.89) 2.58 (0.65) 3.64 (1.04) a***, b***
#Monocytes 0.49 (0.12) 0.48 (0.10) 0.64 (0.25) a**, b***
#Neutrophils 2.87 (0.98) 2.85 (1.06) 4.34 (2.33) a**, b**
#Eosinophils 0.20 (0.17) 0.14 (0.22) 0.25 (0.36) 0.26
#Basophils 0.04 (0.04) 0.04 (0.05) 0.06 (0.005) 0.13
&Categorical variables are presented using counts and percentages. #Continuous variables: WBC, Neutrophils, Lymphocytes and Monocytes are presented as mean (SD); Age, Disease duration, RBC, Eosinophils and Basophils are expressed as median (interquartile range). Denote: a, difference between T1D children and controls; b, difference between siblings and controls. *, P < 0.05; **, P < 0.01; *** P < 0.001.
Table 1: Characterisation of study subjects.