Disease/Cancer Antigenic Transgene Animal models/humans Associated Publications
HIV/SIV HIV: Gag, Pol, Nef SIV: Gag, Pol, Nef Env mice, NHP 1. Gabitzsch ES, et al. (2009) Immunol. Lett. 122: 44-51.
2. Gabitzsch ES, et al. (2009) Vaccine 27: 6394–6398
3. Gabitzsch E, et al. (2011) Vaccine 29(45):8101-7
Influenza hemagglutinin (HA), neuraminidase (NA) mice, ferrets 1. Jones F, et al. (2011) Vaccine 29:7020-6
Colon Cancer carcinoembryonic antigen (CEA) mice, humans 1. Osada T, et al. (2009) Cancer Gene Ther. 16: 673–682 2. Gabitzsch ES, et al. (2010) Cancer Immunol Immunother 59: 1131–1135
3. ClinicalTrials.gov: NCT01147965
Breast Cancer HER2/neu mice 1. Gabitzsch E, et al. (2011) Cancer Gene Ther.  18:326-335
Table 1: Applications of the Ad5 [E1-, E2b-] platform technology.