Figure 3: Decreased CD3 expression after Mtb challenge.
A. Fluorescence intensity of CD3 staining at different time points during TB vaccination and after Mtb challenge from a representative animal is demonstrated. Note the increased frequency of CD3low cells after Mtb challenge.
B. The frequency of CD3low cells was increased after Mtb challenge in all animals (p<0.04 in vaccinated 6 animals). C. CD3lowCD4lowCD8- constituted after Mtb challenge the most frequent cell population.