Inhibitors

Samples

1 (IgG) a

2 (IgG) b

3 (IgG) a

5 (IgG) b

7 (IgM) b

10% TFβ

0.04

0.12

0.03

0.31

3.03

pAA

0.04

UD

0.04

0.09

UD

10% TF

0.63

5.10

0.88

UD

NT

20% TF

1.79

0.90

2.25

NT

UD

20% Tn

2.32

UD

2.84

UD

NT

20% GA1-PAA

2.05

0.59

UD

UD

1.24

20% Gb5tri-PAA

UD

1.44

UD

0.56

1.18

Free TF-sp

UD

82

UD

UD

UD

Free Gb5tri

UD

46

NT

UD

UD

GA1 glycolipid

UD

58

NT

NT

NT


a Antibodies isolated on the TF-PAA-sorbent. Inhibitors are pAA carrier or pAA conjugated glycans except GA1-PAA. The 10% TFβ-pAA was adsorbed onto the plate.
b Antibodies isolated on the TF-sp-sorbents. Inhibitors are the pAA carrier or PAA conjugated glycans. The 10% TFβ-PAA was adsorbed onto the plate.
NT - not tested. UD - undeterminable.
Table 4: The IC50 values (μM) of ligands to antibodies isolated on TF-sorbents.