Parameters after 3 cycles of  RTX

Fixed retreatment
n:57

Non Fixed
n:37

Relative risk
( 95% confidence intervals)

% patients with low IgG

4.3

15.3

3.08 (0.48-8.65)

% patients with normal IgG and infections

5.26

10.81

2.05 (0.07-8.19)

% patients with low IgG and infections

3.50

2.70

0.77 (0.07-8.19)

Patients with low IgG and withdrew because of infections

4.6/100 p/y

1.36/100 p/y

(0.59-6.23)

Table 3: Relationship between the presence or absence of low IgG levels with infections and with withdrawal from the study.