Extract IC50(μg/mL) Monophenolase IC50(μg/mL)Diphenolase IC50(μg/mL) Antioxidant
Methanol 323.11 ± 9.0 1926.03 ± 81 10.61±2.1
Chloroform -* -* -*
n-hexane -* -* -*
Aqueous -* -* -*
Kojic acid 46 ± 0.9 204.08 ± 0.9  
Ascobate Acid     2.11 ± 0.6
Note: IC50 =Concentration of extract can inhibit tyrosinase activity as much as 50%: -* :it didn’t achieve 50% inhibition at maximum concentration of 2000 μg/mL. For antioxidant activity can achieve 50% inhibition at maximum concentration of 100 μg/mL.
Tabel 2: Tyrosinase IC50 value of three extracts from X. granatum seed kernel.