Extract |
IC50(μg/mL) Monophenolase |
IC50(μg/mL)Diphenolase |
IC50(μg/mL) Antioxidant |
Methanol |
323.11 ± 9.0 |
1926.03 ± 81 |
10.61±2.1 |
Chloroform |
-* |
-* |
-* |
n-hexane |
-* |
-* |
-* |
Aqueous |
-* |
-* |
-* |
Kojic acid |
46 ± 0.9 |
204.08 ± 0.9 |
|
Ascobate Acid |
|
|
2.11 ± 0.6 |
|
Note: IC50 =Concentration of extract can inhibit tyrosinase activity as much as 50%: -* :it didn’t achieve 50% inhibition at maximum concentration of 2000 μg/mL. For antioxidant activity can achieve 50% inhibition at maximum concentration of 100 μg/mL. |
Tabel 2: Tyrosinase IC50 value of three extracts from X. granatum seed kernel. |