Inducer IL-4 IL-10
None < 0.1 < 0.5
HSV-2 41 ± 6.1 35 ± 4.8
γ-PGA-APA 400 μg/ml < 0.1 < 0.5
γ-PGA-APA 400 μg/ml+ HSV-2 14 ± 4.1* 7 ± 3.9*
*Significantly different (p<0.05) compared with HSV-2 infected PBMC.
Table 4: Production of Th2 cytokines (IL-4 and IL-10) (pg/ml) at 48 h post γ-PGAAPA treatment by PBMC and under the effect of HSV-2 infection (in grey). Values are expressed as the mean of four experiments ± SD.