| Drug used in Standard regimens for new TB patients |
| (presumed, or known, to have drug-susceptible TB) |
| Intensive phase treatment |
Continuation phase |
| 2 months |
4 months |
| HRZE regimen |
HR regimen |
| Isoniazid (H) |
Isoniazid (H) |
| Rifampicin (R) |
Rifampicin (R) |
| Pyrazinamide (Z) |
|
| Ethambutol (E) |
|
| streptomycin |
|
| In tuberculous meningitis, ethambutol should be replaced by streptomycin. |
| (in settings where the level of isoniazid resistance among new TB cases |
| is high and isoniazid susceptibility testing is not done |
| (or results are not available) before the continuation phase begins |
| Intensive phase treatment |
Continuation phase |
| 2 months |
4 months |
| HRZE regimen |
HRE regimen |
| isoniazid |
isoniazid |
| rifampicin |
rifampicin |
| pyrazinamide |
ethambutol |
| ethambutol |
|
