Drug Classes active in melanoma

Kinase inhibitors

Immunomodulating antibodies

Chemothepateutics Agents

Vaccination

iBRAF

ipilimumab

DTIC

MAGE A3

iMEK

Anti-PD1

TMZ

PRAME

ic-Kit

Anti-CD137

FTM

NY-ISO1

iPI3K

Anti-CD40

CDDP

 

iAKT

OX40

Paclitaxel

IL2 + gp100

imTOR

Anti TGF b

NAB-paclitaxel

 
 

L19IL2

   

PARP inhibitors

Immunomodulating small molecule

Anti-angiogenic Agents

Plasmid/ Oncolytic Virus

ABT-888

1 MT

 

Allovectin-B7

     

Onco-Vex

GSI

HDAC

Pro-apoptotic Drugs

Adoptive Cell therapies

Table 2: