Variable Category n HR 95% CI (HR) P value
Lymph node metastasis No 43 1.0 Reference -
  Yes 52 4.2 2.1 – 8.3 < 0.001
Cyclin A Downregulation 32 1.0 Reference -
  Overexpression (> 3.4) 63 2.3 1.2 – 4.4 0.017
p 21 Downregulation 70 2.4 1.1 – 5.3 0.037
  Overexpression (> 18.4) 25 1.0 Reference -
p 27 Downregulation 13 2.8 1.3 – 5.8 0.007
  Overexpression (> 8.6) 82 1.0 Reference -
Treatment Surgery 35 1.0 Reference -
  Surgery + radiotherapy 60 0.8 0.4 – 1.6 0.541
Age (continuos variable) 95 0.99 0.96 – 1.02 0.544
Table 5: Risk factors for death according to Cox model (final model adjusted for treatment and age).