Genotype χ2 (p)
    CC (n = 26) CT (n = 22) TT (n = 2)
Control CD 40        
Range 4.0 – 11.0 3.0 – 10.0 4.0 – 8.0 3.292 (0.193)
Mean ± SD 6.91 ± 2.30 5.83 ± 2.0 5.44 ± 1.33
Median 6.0 5.0 5.0
p1   0.102 0.112  
p2     0.713  
Asthma CD 40        
Range 2.0 – 18.0 2.0 – 18.0 5.0 – 5.0 7.421* (0.024)
Mean ± SD 9.35 ± 4.54 11.45 ± 4.08 5.0 ± 0.0
Median 9.0 12.0 5.0
p1   0.038 0.087  
p2     0.065  
COPD CD 40        
Range 3.0 – 15.0 2.0 – 17.0 3.0 – 4.0 9.652* (0.008)
Mean ± SD 7.67 ± 3.90 9.81 ± 4.41 3.50 ± 0.58
Median 7.0 10.0 3.50
p1   0.126 0.015*  
p2     0.003*  
p: p value for Mann Whitney test between control and other groups. *: Statistical significance at p ≤ 0.05
Table 5: The comparison of CD40 expression levels on CD20+ B cells possessing different genotypes for -1C > T SNPs of CD40 in each of the studied groups