Fold(HCC versus hepatitis/cirrhosis)by SAM

Cellular Component

Molecular Function

Biological Process






extracellular space, cytoplasm, plasma membrane, caveola, external side of plasma membrane, anchored to membrane, neuron projection

calcium ion binding, low-density lipoprotein binding, protein homodimerization activity, cadherin binding, adiponectin binding

positive regulation of endothelial cell proliferation, positive regulation of cell-matrix adhesion, sprouting angiogenesis, homophilic cell adhesion, negative regulation of cell adhesion, Rho protein signal transduction, negative regulation of cell proliferation, calcium-dependent cell-cell adhesion, Rac protein signal transduction, lamellipodium biogenesis, regulation of endocytosis, positive regulation of cell migration, regulation of epidermal growth factor receptor signaling pathway, endothelial cell migration, keratinocyte proliferation, positive regulation of survival gene product activity, positive regulation of smooth muscle cell proliferation, positive regulation of calcium-mediated signaling, positive regulation of positive chemotaxis, localization within membrane, low density lipoprotein mediated signaling


cell-cell adhesion


Table 2: CDH13 relative fold changes in expression of HCC versus no-tumor hepatitis/cirrhosis by SAM and interpretation by molecule annotation system.