The Study Group Self Antigens
BK AII VEGF bFGF
ISOTYPE of NATURAL ANTIBODIES
IgG IgM IgG IgM IgG IgM IgG IgM
Patients with
osteoarthritis
of the knee
689 ± 161 287 ± 84 409 ± 111 289 ± 99 669 ± 241 559 ± 198 689 ± 245 521 ± 222
100% 77% 71% 66% 59% 79% 35% 61%
Healthy
Individuals
501 ± 98 407 ± 115 274 ± 84 455 ± 101 471 ± 189 366 ± 181 455 ± 115 705 ± 239
Significance P value 0.0001 0.0004 0.0005 0.0001 0.0003 0.005 0.009 0.007
Table 3: Serum expression of natural antibodies against endogenous mediators.