Probe set ID Gene ID Gene title *average of fold changes (2-ΔΔCt) Trend of the changes to the control
5μmol/l 20μmol/l 40μmol/l
neurotoxicity
Pr125404.1 627 Brain-Derived Neurotrophic Factor (BDNF) 0.68 0.48 0.24
Pr132072.1 1809 Dihydropyrimidinase-Like 3 (DPYSL3) 0.74 0.18 0.002
Pr172403.1 2556 Gamma-Aminobutyric Acid (GABA) A Receptor, Alpha 3 (GABRA3) 8.40 0.53 0.93  
Pr001192959.1 342035 Gliomedin (GLDN) 0.14 0.24 0.31  
Pr149117.1 2861 G Protein-Coupled Receptor 37 (GPR37) 5.88 1.63 7.41
Pr169768.1 9783 Regulating Synaptic Membrane Exocytosis 3 (RIMS3) 1.13 6.20 4.54
Pr129608.1 3354 5-Hydroxytryptamine Receptor 1E(HTR1E) 0.42 0.22 0.28  
Pr153563.1 246213 Solute Carrier Family 17 Member 8 (SLC17A8) 0.84 0.26 0.16
transcription
Pr006603767.1 256297 Pancreas Transcription Factor 1 Subunit Alpha (PTF1A) 2.77 2.8 2.14
Pr000110.1 54892 Non-SMC Condensin II Complex, Subunit G2 (NCAPG2) 2.76 0.21 0.49  
Pr138264.1 7832 B-Cell Translocation Gene 2 (BTG2) 0.87 0.65 0.46
Pr135451.1 5585 Protein Kinase N1 (Pkn1) 2.56 0.11 0.54  
Pr161502.1 5162 Pyruvate Dehydrogenase (Lipoamide) Beta (Pdhb) 0.66 0.14 0.06
apoptosis
Pr181057.1 27063 Ankyrin Repeat Domain-containing protein 1 (ANKRD1) 0.2 0.14 0.13
reproductive toxicity
Pr143524.1 353189 Solute Carrier Organic anion transporter family, member 4C1 (SLCO4C1) 0.34 0.20 0.11
Pr001042985.1 27285 Testicular Tektin B1-Like Protein (TEKT2) 0.27 0.14 0.11
Table 1: Validation of gene expression changes by Real-time RT-PCR.