Characteristics Cases N=154(%) Wild type TT N=114(%) Heterozygous TG N=38(%) Homo mutant GG N=2(%) P-Value

Age of Diagnosis
21-30
31-40
41-50
51-60
61-70


16(10%)
38(25%)
50(32%)
38(25%)
12(8%)

10(63%)
22(58%)
42(84%)
28(74%)
12(100%)

6(37%)
14(37%)
8(16%)
10(26%)
0(0%)

0(0%)
2(5%)
0(0%)
0(0%)
0(0%)

0.22
0.03
0.07
0.82
0.12

Body mass index(BMI) status
Normal weight >18.50 to <24.99
Overweight >25 to <29.99
Obese >30.00


30(19%)
40(26%)
84(55%)

20(67%)
29(73%)
65(86%)

9(30%)
11(27%)
18(14%)

1(3%)
0(0%)
1(0%)

0.17
0.38
0.06

Age at Menarche
11-12
13-14
15-16


52(34%)
84(54%)
18(12%)

37(71%)
64(76%)
13(72%)

13(25%)
20(24%)
5(28%)

2(4%)
0(0%)
0(0%)

0.84
0.70
0.77

Menopausal Status
Post Menopausal
Pre Menopausal


80(52%)
74(48%)

65(81%)
49(66%)

15(19%)
23(31%)

0(0%)
2(3%)

0.06
0.06

Estrogen Receptor status
ER+ /PR+
ER+/PR-
ER-/PR+
ER-/PR-


48(31%)
10(7%)
6(4%)
90(58%)

38(79%)
4(40%)
6(100%)
66(73%)

10(21%)
6(60%)
0(0%)
22(25%)

0(0%)
0(0%)
0(0%)
2(2%)

0.42
0.01
0.30
1.00

Her2 status
Her2+
Her2-


135(88%)
19(12%)

100(74%)
14(74%)

33(24%)
5(26%)

2(2%)
0(0%)

0.88
0.88

Chemotherapy
5FU,Adriamycin,Endoxane
Hormonal therapy
RD
No Data


108(70%)
11(7%)
28(18%)
7(5%)

84(78%)
9(82%)
15(54%)
6(86%)

22(20%)
2(18%)
13(46%)
1(14%)

2(2%)
0(0%)
0(0%)
0(0%)

0.06
0.59
0.005
0.51
Table 5: Correlation of breast cancer patient’s demographic factors and ADIPOQ +45G/T genotype frequencies.