Characteristics Cases N=154(%) Wild type GG N=86(%) Heterozygous GT N=64(%) Homo mutant TT N=4(%) P-Value

Age of Diagnosis
21-30
31-40
41-50
51-60
61-70


16(10%)
38(25%)
50(32%)
38(25%)
12(8%)

6(38%)
20(53%)
32(64%)
22(58%)
6(50%)

10(62%)
16(42%)
18(36%)
14(37%)
6(50%)

0(0%)
2(5%)
0(0%)
2(5%)
0(0%)

0.16
0.35
0.005
0.06
1.00

Body mass index(BMI) status
Normal weight >18.50 to <24.99
Overweight >25 to <29.99
Obese >30.00

  
30(19%)
40(26%)
84(55%)

17(57%)
22(55%)
47(57%)

13(43%)
18(45%)
33(33%)

0(0%)
0(0%)
4(10%)

0.14
0.37
0.03

Age at Menarche
11-12
13-14
15-16


52(34%)
84(54%)
18(12%)

34(65%)
48(57%)
4(22%)

16(31%)
36(43%)
12(67%)

2(4%)
0(0%)
2(11%)

0.0005
0.06
0.01

Menopausal Status
Post Menopausal
Pre Menopausal


80(52%)
74(48%)

48(60%)
38(51%)

30(38%)
34(46%)

2(2%)
2(3%)

0.004
0.51

Estrogen Receptor status
ER+ /PR+
ER+/PR-
ER-/PR+
ER-/PR-


48(31%)
10(7%)
6(4%)
90(58%)

28(58%)
8(80%)
4(67%)
46(51%)

20(42%)
2(20%)
2(33%)
40(44%)

0(0%)
0(0%)
0(0%)
4(5%)

0.10
0.01
0.25
0.37

Her2 status
Her2+
Her2-


135(88%)
19(12%)

78(58%)
8(42%)

54(40%)
10(53%)

3(2%)
1(5%)

0.003
0.50

Chemotherapy
5FU,Adriamycin,Endoxane
Hormonal therapy
RD
No Data


108(70%)
11(7%)
28(18%)
7(4%)

62(57%)
6(55%)
16(57%)
2(29%)

42(39%)
5(45%)
12(43%)
5(71%)

4(4%)
0(0%)
0(0%)
0(0%)

0.006
0.67
0.28
0.12
Table 6: Correlation of breast cancer patients demographic factors and ADIPOQ +45G/T genotype frequencies.