Figure 6: Hierarchically clustered heat map of the 37-gene expression signals from ex-vivo TGF-β1 stimulated PBMCs, vehicle controls (PBMCs with no addition) and whole blood from 28 cancer patients and normal subjects. Two major clusters were seen, a TGF-βPI pathway activated block to the left with all the ex-vivo TGF-β1 stimulated samples and a block to the right with majority of normal (Tempus) and vehicle controls designated as pathway not-activated. A central block with intermediate expression was designated partially activated based on signal intensities.