Figure 1: Comparison of serum HB-EGF concentrations determined by immuno-PCR method between healthy volunteers (n=20) and patients of various types of cancers (n=10 of each).
The lower limit of quantification was 5 pg/mL, and serum HB-EGF concentrations below the limit of quantification were regarded as 5 pg/mL. Open circles represent the individual HB-EGF concentrations. Bars indicate mean. The results of t test suggested that there was a statistically significant difference between the values of healthy volunteers and patients of colon, breast, ovarian, head and neck, and pancreatic cancers (P<0.05, Welch’s t test). (H&N: Head and neck, NSCL: Non-small cell lung, SCL: Small cell lung)