Variables Colorectal cancer (n=204) Healthy control (n=10) P value
Age (yr) 64.4 ± 11.8 65.4 ± 3.1 0.447
Male gender 54.4% (111) 60.0% (6) 1.000
WBC count (×103/μl) 7.4 ± 2.5 6.0 ± 2.0 0.063
Hemoglobin (g/dl) 12.2 ± 2.4 14.2 ± 2.0 0.011
CEA (ng/ml) 122.8 ± 626.5 3.3 ± 2.7 0.008
Albumin (g/dl) 4.0 ± 1.4 4.3 ± 0.2 0.483
BUN (mg/dl) 14.0 ± 12.9 14.0 ± 5.2 0.993
Creatinine (mg/dl) 1.0 ± 1.3 0.8 ± 0.2 0.484
Total bilirubin (mmol/L) 0.7 ± 0.3 1.0 ± 0.5 0.124
Phosphate (mg/ml) 3.5 ± 0.9 3.4 ± 0.5 0.664
Alk-P (U/L) 79.5 ± 61.3 59.6 ± 21.3 0.332
AST (IU/L) 28.3 ± 19.5 27.9 ± 6.6 0.943
Lipocalin 2 (ng/ml) 193.3 ± 135.4 36.5 ± 16.1 <0.0001
Stages of colorectal cancer      
I  23.5% (48)  
II 33.8% (69)  
III 24.0% (49)  
IV 18.6% (38)  
Data are expressed as mean ± SD or % (n).
Alk-P: Alkaline Phosphatase; AST: Aspartate Aminotransferase; BUN: Blood Urea
Nitrogen; CEA: Carcinoembryonic Antigen; WBC: White Blood Cell.
Table 1: Baseline Characteristics, Laboratory Findings and Serum Level of Lipocalin 2 in Study Patients and Control Subjects.