Variables Hazard ratio (95% CI) P value CRC stage (I + II + III vs. IV) 9.451 (3.896-22.926) <0.001 Lower level of lipocalin 2 [< 116.7 (ng/ml)] 8.033 (3.160-20.419) <0.001 *Value was used as continuity. † Indicated increased each 1.001 Hazard ratio when CEA increased 10 ng/ml CI: Confidence Interval;

Table 6: Multivariable Stepwise Cox Regression Analysis of Predictors for Cancer Death or Cancer Distal Metastasis during Long-term Follow-up.