Mutation Substitution nucleotide Number of Patients %
p.S549R AGT→AGG at 549 30 65.2
p.∆F508 Deletion of Phe at AA 508 6 13
3120+1G>A G→A- Splice mutation 4 8.7
p.L578delTA TA is deleted from CCTAGAT- Frameshift mutation 2 4.3
p.A357T Ala→Thr at AA 357 1 2.2
3849+10kbC→T C→T, 10kb insertion in intron 19 1 2.2
p.S549R/p.∆F508 Heterozygous 1 2.2
p.∆F508/3120+1G>A Heterozygous 1 2.2
    46 100
Table 1: The CFTR mutation spectrum in Omani population.