Figure 2: Pb-treatment induced RNS-reaction product. (A) Representative APF registrations. In both groups, the APF signal after 5 minutes treatment with Pb had significantly increased (*p<0.05) as a sign of induced RNS-reaction product accumulation. The main effects of treatments (Pb vs. H2O) were significant at level 5%. The significant result (*p<0.05) was marked with asterisk. (B) Photomicrographs of the ROS accumulation (APF-stained HaCat cells) under treatment with Pb at time point 0 and 360 seconds and of H2O treated controls (C) also at time point 0 and 360 seconds (Magnification=400 fold; Bars=10 μm).