Biomarker +/- Count Meta-Score Biomarker +/- Count Meta-Score
SERPINA3 + 5 36 GPX1 - 1 9
TNF Both 6 35 APCS + 1 8
CD40 + 4 34 ENG + 1 8
SERPINA1 + 4 31 CFH + 1 8
EGF Both 3 27 HPX + 1 8
TGFB1 Both 4 27 IL6 + 2 8
IL8 Both 3 23 PECAM1 + 1 8
TTR - 3 22 SELP - 1 8
ICAM1 + 4 21 TF + 1 8
VCAM1 + 2 19 VWF + 1 8
ANGPT2 + 2 19 VCP + 1 8
PDGFB Both 2 18 OLR1 - 1 8
CD40LG + 2 17 SELL - 1 8
CCL15 Both 2 17 ANG - 1 7
SELE + 2 16 BDNF + 1 7
TNFRSF1A + 2 16 CSF3 - 1 7
CRP Both 2 15 IL11 + 1 7
CCL5 Both 2 15 IL3 - 1 7
IL6ST + 2 15 IL1A - 1 7
A2M + 2 14 CCL7 - 1 7
ANGPT1 + 2 14 MDK + 1 7
CLSTN1 + 2 14 CLU - 1 7
MMP9 + 1 13 APOA1 - 1 7
C4A + 2 13 GDNF - 1 7
IL10 + 1 13 PRKACA - 1 7
IGFBP2 + 1 13 PZP + 1 7
VEGFA + 2 13 GC + 1 6
TIMP1 + 1 13 IFNG + 1 6
TNFRSF14 + 1 13 CCL2 + 1 6
IL17A - 1 13 ITIH4 - 1 6
B2M + 1 12 CHI3L1 + 1 6
CCL3 + 1 12 CXCL9 + 1 6
LRP1 - 1 11 NCAM1 + 1 5
CSF1 Both 2 11 MIF + 1 5
EGFR - 1 11 LEP - 1 5
GGT1 + 1 11 KITLG + 1 5
AGER - 1 11 CCL11 + 1 5
ADIPOQ Both 2 11 CST3 + 1 5
MMP2 - 1 10 APOC2 - 1 5
IL1B + 2 10 CCL27 + 1 4
APOE - 1 9 DKK3 + 1 4
DSP + 1 9 SERPINC1 + 1 3
SOD1 - 1 9 APOA4 + 1 3
AMBP + 1 9 FAS + 1 3
IL18 + 1 9 HMOX1 - 1 3
IL16 - 1 9 TNFRSF11B + 1 3
TARDBP + 1 9 ADNP - 1 3
NPPB + 1 9        
+/- indicates the pattern of increase or decrease in blood of AD patients compared to control. Count indicates the number of articles that deal with each biomarker. If one biomarker was reported by multiple articles, the meta-scores evaluated in each article were added (final meta-score). The names of all biomarkers were retrieved from official gene symbol of HPRD
Table 3: The list of meta-scored BBs.