Parameters Mild-moderate UC Group I (n=27) Severe UC Group II (n=23) Control Group Group III (n=10)  P-value
-IL-23 R expression %    
.PBMC 6 12 1c 0.037*
.LPMC 20 29 6a 0.001*
-S IL-23 (pg/ml) 48.9 ± 7.6 137.4 ± 45.5b 23.2 ± 9.4a <0.001*
-IL-23 p 19 expression 11.6 ± 3.4 19.6 ± 5.5b 3.5 ± 1.6a <0.001*
Immunohistochemestry% of +ve cells
P<0.05*significant between all groups; asig between patients & control; bsig between GI & GII. csig between GII & control; UC: ulcerative colitis; PBMC: peripheral blood mononuclear cells (lymphocyte) LPMC: lamina propria mononuclear cells (lymphocyte).
Table 3: IL-23 R expression, serum IL-23 and IL-23p19 expression in the studied groups