Patients characteristics Anti P53 positive antibodies Anti P53 negative antibodies P value
No. (17) No. (122)
Age
< or equal 56 years
>56 years
6 11 80 42 0.016*
Sex
Male
Female
10
7
109
13
0.001*
Alpha fetoprotein
<20
20-400
>400
-
-
17
10
27
85
0.03*
MIF
Low
high
10
61
7
61
0.495
Cirrhosis
Present
Absent
11
6
45
77
0.732
Viral hepatitis
Present
Absent
6
11
82
40
0.011*
BCLC
A1
A2
A3
A4
B
C
D
5
2
1
2
2
3
2
23
29
23
12
4
17
14
0.431  
Portal vein thrombosis
Yes
No
11
6
52
70
0.073
Serum bilirubin
≤1.1
>1.1
4
13
55
67
0.092  
ALP
20-140IU/l
>140 IU/L
3
14
44
78
0.133
AST
≤40
>40
3
14
20
102
0.896
ALT
≤40
>40
3
14
21
101
0.965
Albumin level
3.5-5.5g/L
<3.5gm/L
4
13
48
74
0.207
Prothrombin time(PT)
9.5-13.5 sec
>13.5 sec
5
12
77
45
0.008*
Number of tumors
Single
Multiple
6
11
47
75
0.797
Size of tumor
<5 cm
5 cm-less than 50%
More than 50%
5
6 6
32
54 36
0.799  
Hepatic metastases
No
Yes
16
1
104
18
0.318
Treatment
surgical resection
radiofrequency
TACE
Chemotherapy
No treatment
3
2
3
5
7
2
8
16
2
31
3
64
0.154  
Correlation of different prognostic factors with anti p53 antibody