Figure 2: Genomic distribution of the differentially methylated CpGs sites in low level benzene exposure workers compared with health controls with respect to functional genomics distribution (promoter, gene body, 3′UTR and intergenic) and CpG content (CpG island, shore, shelf and open sea). The location of differentially methylated CpG loci with respect to CpG content and functional genomics distribution was similar in our study, with the majority of CpG loci residing in CpG islands and in gene promoters.