| Gene symbol |
Gene symbol Description |
betweenness centrality |
degree |
Regulation stytle |
| KRAS |
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
0.0377 |
6 |
low |
| RASGRF2 |
Ras protein-specific guanine nucleotide-releasing factor 2 |
0.0348 |
4 |
low |
| JUN |
jun proto-oncogene |
0.0261 |
4 |
high |
| CACNA1H |
calcium channel, voltage-dependent, T type, alpha 1H subunit |
0.0239 |
2 |
high |
| RYR3 |
ryanodine receptor 3 |
0.020 |
3 |
low |
| KIT |
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
0.010 |
4 |
high |
|
| The degree is defined as the sum of connection strengths with the other network genes. For a gene in the network, the number of source genes of a gene is called the
indegree of the gene and the number of target genes of a gene is its outdegree. The character of genes is described by betweenness centrality measures reflecting the
importance of a node in a graph relative to other nodes |
| Table 3: The top 6 significantly methylated genes according to the degree size Supporting Information. |
