Cancer type Cell line EpCAM antibody EpCAMaptamer
Pancreatic cancer PANC-1 ++ ++
ASPC-1 ++ ++
PANC-28 + +
Breast cancer MDA-MB-231 ++ ++
MDA-MB-468 ++ ++
BT-474 + +
SKBR3 ++ ++
Ovarian cancer OVCAR3 + +
SKOV3 + +
Hey + +
Prostate cancer DU145 ++ ++
22RV1 + +
VCap + +
PC3 + +
Colon cancer HT29 ++ ++
Epithelial cells 293T ++ ++
HeLa + +
Chronic myelogenous leukemia K562 ++ ++
Burkitt’s lymphoma CA46 - -
Mantle Cell Lymphoma Jeko-1 - -
Mantle Cell Lymphoma Maver-1 - -
Acute Myeloid Leukemia HEL - -
Histiocytic lymphoma U937 - -
Note: “++” EpCAM overexpression, “+” EpCAM -positive, “-” EpCAM-negative
Table 1: Summary of EpCAM aptamer binding to differentiate cancer cells.