MetS (n=60) No MetS (n=62) p-value p-valuea Age (years) 58 ± 9 55 ± 10 0.07   Gender (men/women) 32/28 32/30 0.99   Diabetes (yes/no) 48/12 18/44 <0.001   Systolic blood pressure (mm Hg) 146 ± 19 131 ± 22 <0.001 <0.001 Diastolic blood pressure (mm Hg) 89 ± 9 81 ± 11 <0.001 <0.001 BMI (kg/m2) 30.1 ± 4.6 25.1 ± 3.5 <0.001 <0.001 Waist circumference (cm) 104 ± 13 86 ± 11 <0.001 <0.001 Glucose (mmol/L) 8.7 ±2.5 6.3 ± 1.5 <0.001 0.011 HbA1c (mmol/mol) 48 ±9 39 ± 5 <0.001 0.61 APOE genotype ε2/ε3 ε3/ε3 ε3/ε4 ε4/ε4   4 38 14 4   2 49 11 0 0.091   Total cholesterol (mmol/L) 5.54 ± 0.95 5.56 ± 0.0.96 0.92 0.26 LDL cholesterol (mmol/L) 3.37 ± 0.86 3.36 ± 0.83 0.97 0.33 Non-HDL cholesterol (mmol/L) 4.33 ± 0.95 3.98 ± 1.04 0.057 0.006 HDL cholesterol mmol/L) 1.21 ± 0.36 1.58 ± 0.39 <0.001 <0.001 Triglycerides (mmol/L) 1.95 (1.70-2.52) 1.15 (0.85-1.59) <0.001 <0.001 ApoA-I (g/L) 1.32 ± 0.25 1.46 ± 0.20 0.001 <0.001 ApoB (g/L) 0.98 ± 0.22 0.90 ± 0.23 0.037 0.007 ApoE (g/L) 0.042 ± 0.012 0.037 ± 0.009 0.008 0.006 Data in mean ± SD or in median (interquartile range). Apo: apolipoproteins; BMI: body mass index; HbA1c, glycated hemoglobin; HDL: high density lipoproteins; LDL: low density lipoproteins; non-HDL: non-high density lipoproteins. LDL cholesterol was calculated in 57 subjects with and in 60 subjects without MetS. ap-value: p-value after adjustment for age, sex and diabetes status.

Table 1: Clinical characteristics, plasma glucose, glycated hemoglobin (HbA1c), apolipoproten E (apoE) genotype, plasma lipids, apolipoproteins (apos) and lipoprotein subfractions in 60 subjects with and in 62 subjects without metabolic syndrome (MetS).