| |
HR (95% CI) (unadjusted) |
P-value (unadjusted) |
HR (95% CI) (adjusted) |
P-value (adjusted) |
| 2a CRPC |
|
|
|
|
| ERG expression/PTEN deletion*/GS≥8 |
19.43 (1.73-218.17) |
0.016 |
40.445 (2.94-557.32) |
0.006 |
| 2b PCa specific death |
|
|
|
|
| ERG expression/PTEN deletion*/ GS≥8 |
17.99 (1.57-205.66) |
0.020 |
64.21 (4.22-976.52) |
0.003 |
| ERG expression/EZH2 expression/PTEN deletion** |
ns |
|
40.70 (2.00-827.98) |
0.016 |
| ERG expression/PTEN deletion** |
ns |
|
44.05 (2.01-964.37) |
0.016 |
* Hetero-or homozygous deletion
** Heterozygous deletion
Adjusted for PSA at diagnosis, T-stage, Gleason score, age at diagnosis, calendar year of diagnosis GS=Gleason score, ns=not significant |
|
