Gene aSLE(32) control(60) OR 95%CI P value
ESR1 TT 7(21.9) 6(10.0) 1(reference) - -
TC 14(43.8) 28(46.7) 0.889 0.375-2.107 0.829
CC 11(34.4) 26(43.3) 0.685 0.281-1.669 0.504
T 28/64(43.8) 40/120(33.3) 0.643 0.345-1.19 0.163
C 36/64(56.3) 80/120(66.7)
ESR2 GG 17(53.1) 14(23.3) 1(reference) - -
GA 13(40.6) 14(23.3) 2.248 0.891-5.669 0.097
AA 2(6.3) 32(53.3) 0.058 0.013-0.266 0.000*
G 47/64(73.4) 42/120(35.0) 0.195 0.1-0.38 0.007*
A 17/64(26.6) 78/120(65.0)
*P is only statistically significant if ≤0.05
Table 2: Comparison between aSLE patients and controls as regards the frequencies of ESR1 and ESR2 genotypes and alleles.