| |
Gene |
aSLE(32) |
control(60) |
OR |
95%CI |
P value |
| ESR1 |
TT |
7(21.9) |
6(10.0) |
1(reference) |
- |
- |
| TC |
14(43.8) |
28(46.7) |
0.889 |
0.375-2.107 |
0.829 |
| CC |
11(34.4) |
26(43.3) |
0.685 |
0.281-1.669 |
0.504 |
| T |
28/64(43.8) |
40/120(33.3) |
0.643 |
0.345-1.19 |
0.163 |
| C |
36/64(56.3) |
80/120(66.7) |
| ESR2 |
GG |
17(53.1) |
14(23.3) |
1(reference) |
- |
- |
| GA |
13(40.6) |
14(23.3) |
2.248 |
0.891-5.669 |
0.097 |
| AA |
2(6.3) |
32(53.3) |
0.058 |
0.013-0.266 |
0.000* |
| G |
47/64(73.4) |
42/120(35.0) |
0.195 |
0.1-0.38 |
0.007* |
| A |
17/64(26.6) |
78/120(65.0) |
|
| *P is only statistically significant if ≤0.05 |
| Table 2: Comparison between aSLE patients and controls as regards the
frequencies of ESR1 and ESR2 genotypes and alleles. |
