Gene jSLE(33) control(60) OR 95%CI P value
ESR1 TT 4(12.1) 6(10.0) 1(reference)    
TC 17(51.5) 28(46.7) 0.911 0.224-3.698 0.896
CC 12(36.4) 26(43.3) 0.692 0.164-2.917 0.616
T 26/66(39.4) 40/120(33.3) 0.82 0.43-1.53 0.534
C 40/66(60.6) 80/120(66.7)
ESR2 GG 13(39.4) 14(23.3) 1(reference)    
GA 12(36.4) 14(23.3) 0.923 0.314-2.716 0.884
AA 8(24.2) 32(53.3) 0.269 0.091-0.794 0.017*
G 38/66(57.6) 42/120(35.0) 0.397 0.214 – 0.734 0.003*
A 28/66(42.4) 78/120(65.0)
*P is only statistically significant if ≤0.05.
Table 3: Comparison between jSLE patients and controls as regards the frequencies of ESR1 and ESR2 genotypes and alleles.