| |
Gene |
jSLE(33) |
control(60) |
OR |
95%CI |
P value |
| ESR1 |
TT |
4(12.1) |
6(10.0) |
1(reference) |
|
|
| TC |
17(51.5) |
28(46.7) |
0.911 |
0.224-3.698 |
0.896 |
| CC |
12(36.4) |
26(43.3) |
0.692 |
0.164-2.917 |
0.616 |
| T |
26/66(39.4) |
40/120(33.3) |
0.82 |
0.43-1.53 |
0.534 |
| C |
40/66(60.6) |
80/120(66.7) |
| ESR2 |
GG |
13(39.4) |
14(23.3) |
1(reference) |
|
|
| GA |
12(36.4) |
14(23.3) |
0.923 |
0.314-2.716 |
0.884 |
| AA |
8(24.2) |
32(53.3) |
0.269 |
0.091-0.794 |
0.017* |
| G |
38/66(57.6) |
42/120(35.0) |
0.397 |
0.214 – 0.734 |
0.003* |
| A |
28/66(42.4) |
78/120(65.0) |
|
| *P is only statistically significant if ≤0.05. |
| Table 3: Comparison between jSLE patients and controls as regards the
frequencies of ESR1 and ESR2 genotypes and alleles. |
