Negative No.(%) Mild No.(%) Moderate No.(%) Marked No.(%) P value bcl-2 expression (I.H) Positive bcl-2 Negative bcl-2 1 (25.0%) 3 (75.0%) 8 (47.1%) 9    (47.4%) 18/40   (45.0%) 0.69 9 (75.0%) 10   (52.6%) 22/40   (55.0%)   Serum bcl-2 antigen Positive bcl-2 2   (28.6%) 4   (22.2%)   7   (35.0%) 13/45   (28.9%)   Negative bcl-2 5   (71.4%) 14  (77.8%) 13  (65.0%) 32/45   (71.1%) 0.57

Table 4: Correlation between Apoptotic index (AI) (negative, mild, moderate, marked) serum Bcl-2 protein expression in 45 patients and immunostaining in 40 patients with gastric cancer.