Figure 2: KEGG pathways significantly enriched in target genes of the 7 miRNAs alteredin blood of obese patients vs healthy lean subjects. Target gene prediction and predicted KEGG pathways are from miRPath (26). MiR-221 did not significantly targeted a specific KEGG pathways. In red, KEGG pathways down-regulated and targeted by up-regulated circulating miRNAs; in green, KEGG pathways upregulated and targeted by downregulated miRNAs.