Organism Metabolite/ compound Source Activity Reference Bacteria Brevibacteriumsp., Moraxella sp., Cornyebacteriumsp., Crude extracts Sediment of Gulf of Aqaba, Red sea Antibacterial andantioxidant  [44] Vibrio sp., Aqabamycins A-G From the surface of coral (Sinulariapolydactyla)  Red sea Antibacterial and cytotoxic [23] Halophilicsp., Chromohalobactersalexigens, Halomonas meridian, Idiomarinaloihiensis, Chromohalobacterisraelensis Crude extract Brine pools of the Red sea and from sediment Anticancer  [29] Halomonas Sulfitobacter Crude extract Brine-seawater interface of the Red Sea Anticancer [28] Carteriospongia sp. and Dysidea sp. Scalaranesesterterpenes Marine sponge Phyllo- spongialamellosa collected from the Red Sea  Antibacterial and cytotoxic [135] Gammaproteobacteria, Actinobacteria and Firmicutes Crude extracts Soft coral Sarcophytonglaucum from the Red sea Antibacterial and antifungal [136] Nocardia sp. Chrysophanol 8-methyl ether, Asphodelin; 4,7'-bichrysophanol, Justicidin B, Ayamycin Ras-Gharib coast of theRed Sea, Egypt Antibacterial and antifungal [137] Vibrio sp. II Aqabamycins A–G Red Sea Antibacterial and cytotoxic  [138] Actinomycetes Crude extracts Sponges offshore Fsar reef Red sea Antibacterial, antifungal and antiviral  [43] Fungi Aspergillusversicolor Isorhodoptilometrin-1-methyl ether, Emodin, 1-methyl emodin, Evariquinone, 7-hydroxyemodin 6,8-methyl ether, Siderin, Arugosin C and Variculanol Red Sea Antibacterial, antifungal and Antiviral (HCV)  [38]

Table 1: List of the Red sea microbial diversity, their natural products, and their biological activities.