Variable OS (n = 36)
First Node No bone marrow infiltration (n = 31) Bone marrow infiltration (n = 5)
Second Node IRF8 low
(n = 16)
IRF8 high
(n = 15)
Stage ≤ 3
(n = 3)
Stage = 4
(n = 2)
ThirdNode ITI = 1
(n = 7)
ITI ≥ 2
(n = 9)
ITI = 1
(n = 3)
ITI ≥ 2
(n = 12)
-------------- Male
(n = 1)
Female
(n = 1)
Table 4: The IRF8 expression at diagnosis provides valuable information to discriminate among the clinically considered low risk
DLBCL patients. IRF8 expression predicts outcome among this group of DLBCL patients in terms of overall survival.