Group 1a (N=86)   Sd Min Max Cv CI OC1 26.59 11.62 4.1 56.6 43.70 24.10-29.08 CL1 428.59 232.63 18.8 1038.0 54.28 378.70-478.48 Group 2a (N=92)   Sd Min Max Cv CI OC1 36.64 11.89 13.0 78.9 32.44 34.18-39.10 CL1 665.88 248.51 204.0 1290.0 37.32 614.41-717.36 Asymmetry and flattening values ranging from -.04 to .04 were not discussed Minimal (min) i maximal (max) biochemical markers of participants in group 1a indicate that values are within the expected range. Larger values of the coefficient of variation (Cv) indicate that there is heterogeneity of Group 1a in terms of: OC1 (OC1) (43.70), CL1 (CL1) (54.28). Increased values of Skewness indicate that distribution is negatively asymmetric which means that distribution results curve tends toward larger values, i.e., there are larger values in comparison to normal distribution in: OC1 (OC1) (.28), CL1 (CL1) (.15). Negative values of Curtosis indicate that curve is flattened at: OC1 (OC1) (-.56), CL1 (CL1) (-.77). Distribution of values range mostly within normal distribution (p) in: OC1 (OC1) (.22), CL1 (CL1) (.61) Minimal (min) i maximal (max) biochemical markers of participants in Group 2a indicate that values are within the expected range. Larger values of the coefficient of variation (Cv) indicate that there is heterogeneity of the Group 2a in terms of: OC1 (OC1) (32.44), CL1 (CL1) (37.32). Increased values of Skewness indicate that distribution is negatively asymmetric which means that distribution results curve tends toward larger values, i.e., there are larger values in comparison to normal distribution in: OC1 (OC1) (.43), CL1 (CL1) (.60). Larger values of Kurtosis indicate that curve has been elongated at: OC1 (OC1) (.44). Negative values of Kurtosis indicate that curve has been flattened at: CL1 (CL1) (-.05). Value distribution ranges mostly within normal distribution (p) at: OC1 (OC1) (.94), CL1 (CL1) (.57)

Table 5: Central and dispersive parameters and asymmetry and flattening measures of laboratory parameters during the therapy in groups (N=178).