Group MMP-8 (ng/ml) MMP-8/TIMP-1

Area under the curve (95% CI), p

Acutecoronarysyndrome
All 0.729 (0.692-0.767), <0.001 0.707 (0.668-0.746), <0.001
Non-smokers 0.750 (0.707-0.793), <0.001 0.732 (0.688-0.777), <0.001
Smokers 0.620 (0.518-0.721), 0.024 0.621 (0.520-0.722),0.022
Unstableangina
All 0.668 (0.610-0.726), <0.001 0.660 (0.602-0.719), <0.001
Non-smokers 0.714 (0.652-0.776), <0.001 0.707 (0.643-0.771), <0.001
Smokers 0.330 (0.170-0.490), 0.085 0.341 (0.179-0.503), 0.107
Myocardialinfarction
All 0.757 (0.718-0.797), <0.001 0.729 (0.686-0.770), <0.001
Non-smokers 0.771 (0.723-0.818), <0.001 0.746 (0.696-0.795), <0.001
Smokers 0.684 (0.581-0.787), 0.001 0.684 (0.582-0.786),0.001
Table 3: ROC data of serum MMP-8 concentrations and MMP-8/TIMP-1 ratio for ACS according to the smoking status.