| |
AUC (95% CI) |
p value |
Sensitivity (%) at 95% specificity |
Cut off value (95% specificity) |
| IL8 |
0.68 (0.59 - 0.77) |
0.0006 |
38 |
>21.86 |
| Mac2BP |
0.67 (0.58 - 0.76) |
0.0009 |
35 |
>9304 |
| TIMP1 (plasma) |
0.64 (0.55 - 0.73) |
0.0061 |
33 |
>110.5 |
| OPN |
0.61 (0.52 - 0.70) |
0.0329 |
31 |
>11800 |
| TIMP1 (serum) |
0.63 (0.54 - 0.72) |
0.0133 |
28 |
>232.0 |
| IL6 |
0.70 (0.61 - 0.80) |
0.0002 |
27 |
>2.895 |
| M65 |
0.66 (0.56 - 0.75) |
0.0016 |
26 |
>472.4 |
| IGFBP2 |
0.67 (0.57 - 0.76) |
0.0008 |
25 |
>1225 |
| TIMP2 (serum) |
0.58 (0.48 - 0.67) |
0.1144 |
25 |
<64.67 |
| TIMP2 (plasma) |
0.52 (0.43 - 0.62) |
0.6578 |
24 |
<74.65 |
| IGF2 |
0.64 (0.55 - 0.73) |
0.0040 |
23 |
<1040 |
| VEGFA |
0.67 (0.58 - 0.77) |
0.0005 |
23 |
>132.5 |
| CEACAM6 |
0.58 (0.48 - 0.67) |
0.1340 |
22 |
>2.558 |
| TGFB1 |
0.65 (0.56 - 0.74) |
0.0027 |
22 |
>16195 |
| TNF-alpha |
0.58 (0.49 - 0.69) |
0.1088 |
20 |
>11.51 |
| PKM2 |
0.70 (0.60 - 0.79) |
0.0001 |
19 |
>60.39 |
| Dkk3 |
0.50 (0.41 - 0.60) |
0.9502 |
18 |
<42184 |
| MMP1 |
0.62 (0.52 - 0.71) |
0.0226 |
15 |
>9130 |
| M30 |
0.51 (0.41 - 0.61) |
0.8417 |
13 |
>374.2 |
| MMP8 |
0.51 (0.41 - 0.61) |
0.7808 |
12 |
>18650 |
| ENA-78 |
0.54 (0.44 - 0.64) |
0.4705 |
10 |
<488.0 |
| MIP-1beta |
0.56 (0.46 - 0.66) |
0.2245 |
9 |
<26.35 |
| MMP3 |
0.53 (0.44 - 0.63) |
0.5744 |
7 |
<5460 |
| MCP1 |
0.51 (0.41 - 0.61) |
0.7899 |
6 |
>416.0 |
AUC: Area under the receiver operator characteristic curve |
