Figure 2: Receiver operating characteristic (ROC) curves for the ability of
serum Dkk–3 levels to discriminate between healthy controls and patients with
CRC (CRC). At 90% specificity, serum Dkk–3 levels distinguished CRC patients
(all Dukes´ stages) with 36% sensitivity. At 90% specificity, the sensitivity was
24%, 32%, 47% and 38%, respectively for Dukes´ stages A, B, C, and D.
Diagnostic subgroups are denoted as follows: CRC (encompassing all Dukes´
stages) [], Dukes´ A [], Dukes´ B [], Dukes´ C [], Dukes´ D []. The line of
identity is represented by a grey dashed line.