PATIENT ID

AGE

RURAL/
URBAN

CLNICAL TUMOR STAGE

EXON

CODON
NUMBER

NUCLEOTIDE
NUMBER

MUTATION
cDNA SEQUENCE

BASE CHANGE

AMINO ACID
CHANGE

MUTATIONEFFECT

15N

45/M

R

GRADE III

5

169

13185

506delT

ATG>A_G

NS
(Met>Arg)

FS

15T

5

147

13118

439G>T

GTT>TTT

Val>Phe

MS

5

179

13214

535 C>G

CAT>GAT

His>Asp

MS

15L

5

170

13189

510InsT

ACG>ACTG

NS
(Thr>Thr)

FS

5

173

13197

518delT

GTG>G_G

NS
(Val>Gly)

FS

6

213

13397

636C>G

CGA>GGA

Arg>Gly

MS
(at CpG)

Table 2: Clinico-epidemiological details and nature of TP53 mutations in germline gastric adenocarcinoma patients from Kashmir valley.