MUTATION PATTERN DATA (21) (%)

MUTATION EFFECT DATA (21) (%)

Insertions                   12 (57.14%)
Substitution                6 (28.57%)
        
          G:C>T:A                   1 (16.7%)
          A:T>T:A                    1 (16.7%)
          C:G>G:C                   1 (16.7%)
          C:G>G:C at CpG       1 (16.7%)       
          T:A>G:C                    1 (16.7%)
          C:G>A:T                    1 (16.7%)
         
Deletion                      3 (14.3%)

χ2 =  9.00
df= 2
p-value= .001

Missense                    5 (23.8%)
Frame-shift               15 (71.43%)
Silent                          1(4.8%)

 

 

 

 
χ2 = 22.28
df= 2
p-value=.000 

Table 4: Mutation pattern and mutation effect data of TP53 in gastric cancer patients from Kashmir valley.