Gene symbol Repressed Increased Function

BIRC5

x   Inhibitor of apoptosis

BAX

x   Pro-apoptotic mediator

VCP

x   Vesicle transport and fusion

TNFRSF10B

  x Intracellular death domain

TNFRSF10A

  x Intracellular death domain

CYCS

  x Activates the apoptotic initiator procaspase 9
Table 4: Genes in the Go-Term “Regulation of caspase” (GO:0043281) which were found in common in both Affymetrix® and Illumina® array protocols analyzed in PC-3 cells. No such changes were found in DU-145 cells.