Figure 5: Pyelonephritis incidence in hormone-treated mice. (A) H&E staining of a healthy kidney from a 24 week-old WT mouse (left) vs. a kidney displaying pyelonephritis from a 24-week-old tgPim1 mouse, both after 2 rounds of hormone treatment (right). Note the areas of renal infarct in the animal with pyelonephritis, in which more than one-third of the parenchyma is affected. (B) Percentage of pyelonephritis incidence in every genotype after 1 or 2 rounds of hormone treatment, respectively.